What is endometrial scratching?
We are able to offer a treatment called endometrial scratching to try and help your embryo(s) implant by improving the endometrial receptivity. This is achieved by “scratching” your endometrial lining before you start your IVF cycle.
Who may benefit from endometrial scratching?
If you have had good quality embryo(s) transferred on at least 2 occasions with no pregnancy resulting we may suggest that you would benefit from this procedure.
How does scratching help implantation?
There are thought to be two ways that scratching might help your embryo(s) implant: (a) certain genes important in preparing the endometrium for pregnancy become “switched on”, and (b) immune cells in the uterus which help implantation increase in number. These help make the lining more receptive to any embryo(s) that are transferred.
When is it done?
The best time to perform endometrial scratching is 7-14 days before the start of your treatment cycle (around the time down-regulation is commenced).
What is involved?
The procedure is quick and simple and should take no more than 15 minutes. The endometrium (lining of the uterus) is gently “scratched” using a disposable sterile instrument, passed through the cervix.
How successful is endometrial scratching?
Endometrial scratching is a relatively new technique and as such we do not have sufficient data to provide success rates at this centre. Clinical trials at other units suggest improved outcomes for women with previous failed treatment cycles.
There is an additional charge for this procedure – please see our Prices
Pipelle for Pregnancy (PIP) study at Bath Fertility
We are taking part in the PIP studies which is a large randomised controlled clinical trial to look at the effects of endometrial scratch on potentially increasing the chances of pregnancy. Recruitment for the PIP-IVF study has now ended and we would like to thank all of our patients that participated. The study has completed recruiting over 1300 women across five countries and will be the largest trial of endometrial scratching undertaken. Results of the study are expected to be published by the end of 2018.
There are still two more arms of the PIP study that we are currently recruiting for: PIP-unexplained (UE) and PIP-PCOS. PIP-UE is for couples with unexplained infertility who are trying to get pregnant naturally and PIP-PCOS is for couples with subfertility related to polycystic ovarian syndrome, who are on ovulation induction medication. If you are interested in participating in these studies or would like to have some more information on the studies please call us on 01761 438 583 and ask to speak to our Embryologist Emma Napier or email us on firstname.lastname@example.org.